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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
4.55
Human Site:
S375
Identified Species:
7.69
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S375
E
E
L
E
A
A
A
S
H
L
N
K
D
L
Y
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S517
E
E
L
E
A
A
A
S
H
L
N
K
D
L
Y
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
G310
L
Y
R
E
L
L
G
G
T
P
G
S
S
E
A
Dog
Lupus familis
XP_548005
637
70371
D348
F
Y
Q
E
L
L
G
D
S
I
S
S
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
A374
D
E
E
L
E
A
A
A
S
H
M
N
K
D
F
Rat
Rattus norvegicus
NP_001100231
686
74096
A384
D
E
E
L
E
A
A
A
S
H
M
N
K
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
K380
A
A
A
N
H
L
N
K
D
F
C
N
E
L
L
Frog
Xenopus laevis
NP_001088063
660
73751
D367
G
E
E
D
D
D
E
D
L
E
A
A
A
N
H
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
A374
E
D
E
E
M
E
A
A
A
K
H
L
N
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
E373
E
E
S
R
Q
F
I
E
Q
S
N
A
E
V
I
Honey Bee
Apis mellifera
XP_623775
648
73504
I359
R
E
S
N
L
D
V
I
K
N
Y
V
E
N
D
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
E373
G
L
E
K
G
A
D
E
M
V
R
N
E
I
I
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
G442
G
E
K
G
G
E
D
G
A
S
G
A
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
E307
I
K
D
S
L
D
K
E
E
M
F
Q
T
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
6.6
6.6
N.A.
20
20
N.A.
N.A.
6.6
6.6
20
N.A.
20
6.6
6.6
6.6
P-Site Similarity:
100
100
6.6
20
N.A.
40
40
N.A.
N.A.
13.3
20
46.6
N.A.
33.3
13.3
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
15
36
36
22
15
0
8
22
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
15
8
8
8
8
22
15
15
8
0
0
0
15
15
8
% D
% Glu:
29
58
36
36
15
15
8
22
8
8
0
0
29
8
22
% E
% Phe:
8
0
0
0
0
8
0
0
0
8
8
0
0
0
15
% F
% Gly:
22
0
0
8
15
0
15
15
0
0
15
0
8
8
8
% G
% His:
0
0
0
0
8
0
0
0
15
15
8
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
8
8
0
8
0
0
0
8
15
% I
% Lys:
0
8
8
8
0
0
8
8
8
8
0
15
15
0
0
% K
% Leu:
8
8
15
15
29
22
0
0
8
15
0
8
0
22
8
% L
% Met:
0
0
0
0
8
0
0
0
8
8
15
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
8
0
0
8
22
29
8
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
8
0
0
8
0
8
0
% Q
% Arg:
8
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
15
8
0
0
0
15
22
15
8
15
15
15
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
0
8
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _